Research
Interests:
® Structural
and functional study of disease-related membrane proteins (receptors &
ion channels) or solutable proteins using solution & solid state NMR
(Nuclear Magnetic Resonance), EPR (Electron Paramagnetic Resonance) and
biochemical
techniques.
® Site-specific incorporation of unnatural amino acid for protein
structure and function analysis.
® Research
works of quantum simulation and quantum computation on NMR quantum
simulator under high magnetic field condition.
Current
Research Projects:
National Basic
Research Program of China (973 Program):
® The life cycle of proteins and their
molecular mechanism of regulations (Grant: 2012CB917202)
®
Solid-state quantum computation research based on spin quantum
control (Grant: 2013CB921800)
National Natural
Science Foundation of China:
® Quantum simulation on NMR system with high magnetic field (Grant:
11374308 )
® Studies on the conformational change and dynamic process of
phytohormone ABA receptors PYL2/10 upon the binding of ABA using both
NMR and X-ray crystallography (Grant: 31100538)
® Transportation process studies of E. coli glutamate/g-amino
butyric acid antiporter GadC using 19F site-specific labeling
and 19F NMR (Grant: 31300685)
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